Eucomic acid methanol monosolvate
نویسندگان
چکیده
IN THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND [SYSTEMATIC NAME: 2-hy-droxy-2-(4-hy-droxy-benz-yl)butane-dioic acid methanol monosolvate], C(11)H(12)O(6)·CH(3)OH, the dihedral angles between the planes of the carboxyl groups and the benzene ring are 51.23 (9) and 87.97 (9)°. Inter-molecular O-H⋯O hydrogen-bonding inter-actions involving the hy-droxy and carb-oxy-lic acid groups and the methanol solvent mol-ecule give a three-dimensional structure.
منابع مشابه
Catalytic enantioselective total synthesis of (+)-eucomic acid.
A catalytic enantioselective synthesis of (+)-eucomic acid is reported. A palladium-catalyzed asymmetric allylic alkylation is employed to access the chiral tetrasubstituted α-hydroxyacid moiety found in the natural product. The protecting group strategy was investigated, and a protecting group manipulation was made without any appreciable deleterious effects in the allylic alkylation reaction....
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